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Canada is going to throw out about 13.6 million doses of the Oxford-AstraZeneca COVID-19 vaccine because it couldn't find any takers for it either at home or abroad.
Canada signed a contract with AstraZeneca in 2020 to get 20 million doses of its vaccine, and 2.3 million Canadians received at least one dose of it, mostly between March and June 2021.
Following concerns in the spring of 2021 about rare but potentially fatal blood clots from AstraZeneca, Canada focused on using its ample supplies of the mRNA vaccines from Pfizer-BioNTech and Moderna.
In July 2021, Canada promised to donate the rest of its procured supply, about 17.7 million doses. But in a statement Tuesday, Health Canada said that despite efforts to meet that pledge, 13.6 million doses have expired and will have to be thrown out.
"Due to limited demand for the vaccine and recipient country challenges with distribution and absorption, they were not accepted?" the statement said.
In all, Canada donated 8.9 million doses of AstraZeneca vaccine — 4.8 millon doses from its main supply and 4.1 million doses that it bought from the COVAX vaccine-sharing programme.
About 85 per cent of Canadians are considered fully vaccinated, compared with 61 per cent of the world's population, and just 16 per cent of people living in the world's poorest countries

Why Canada is throwing 13.6 million doses of Covid-19 vaccine

About 85 per cent of Canadians are considered fully vaccinated, compared with 61 per cent of the world's population, and just 16 per cent of people living in the world's poorest countries

Canada is going to throw out about 13.6 million doses of the Oxford-AstraZeneca COVID-19 vaccine because it couldn't find any takers for it either at home or abroad.
Canada signed a contract with AstraZeneca in 2020 to get 20 million doses of its vaccine, and 2.3 million Canadians received at least one dose of it, mostly between March and June 2021.
Following concerns in the spring of 2021 about rare but potentially fatal blood clots from AstraZeneca, Canada focused on using its ample supplies of the mRNA vaccines from Pfizer-BioNTech and Moderna.
In July 2021, Canada promised to donate the rest of its procured supply, about 17.7 million doses. But in a statement Tuesday, Health Canada said that despite efforts to meet that pledge, 13.6 million doses have expired and will have to be thrown out.
"Due to limited demand for the vaccine and recipient country challenges with distribution and absorption, they were not accepted?" the statement said.
In all, Canada donated 8.9 million doses of AstraZeneca vaccine &mdash; 4.8 millon doses from its main supply and 4.1 million doses that it bought from the COVAX vaccine-sharing programme.
Also watch: <a href="https://www.editorji.com/world-news/covid-vaccine-finally-reaches-north-korea-country-calls-it-immortal-potion-of-love-from-kim-jong-un-1653926591334">Covid vaccine finally reaches North Korea; country calls it 'immortal potion of love' from Kim Jong Un</a>
About 85 per cent of Canadians are considered fully vaccinated, compared with 61 per cent of the world's population, and just 16 per cent of people living in the world's poorest countries

President of the 76th session of the UN General Assembly Abdulla Shahid has said he received the two doses of the Covishield vaccine manufactured in India
He also added that a &ldquo;large portion&rdquo; of other countries around the world have also received India&rsquo;s Covid-19 vaccine, Covishield.
The Covishield vaccine, developed by AstraZeneca, is manufactured in India by Pune-based Serum Institute of India.
Shahid was responding to a question on whether any Covid-19 vaccine should be recognised and considered or only the ones validated by the World Health Organization or any other group.
Shahid said he took Covishield and &lsquo;survived&rsquo; but added that a &lsquo;someone else, a medical person make that call&rsquo; on recognizing vaccine
India has exported over 66 million vaccine doses to nearly 100 countries through grants, commercial shipments and the COVAX facility.

'I got India's Covishield vaccine': UNGA President Abdulla Shahid

President of the 76th session of the UN General Assembly Abdulla Shahid has said he had received the two doses of the Covishield vaccine manufactured in India

//UNGA president Abdulla Shahid: received 2 doses of Covishield&nbsp;&amp; survived
//Shahid: a &ldquo;large portion&rdquo; of other countries also received Covishield
//Covishield,&nbsp;developed by AstraZeneca, is manufactured by Pune-based SII
//Shahid: a medical person should make that call on recognizing vaccine
//India has exported over 66 million Covid vaccine doses to nearly 100 countries
&nbsp;

India has exported over 66 million vaccine doses to nearly 100 countries through grants, commercial shipments and the COVAX facility.

President of the 76th session of the UN General Assembly Abdulla Shahid has said he received the two doses of the Covishield vaccine manufactured in India
He also added that a &ldquo;large portion&rdquo; of other countries around the world have also received India&rsquo;s Covid-19 vaccine, Covishield.
The Covishield vaccine, developed by AstraZeneca, is manufactured in India by Pune-based Serum Institute of India.
Also Read&nbsp;<a href="https://www.editorji.com/india-news/italy-recognises-india-s-covishield-jabbed-travelers-eligible-for-green-pass-1632489132790" target="_blank">Italy recognises India's Covishield, jabbed travelers eligible for green pass</a>
Shahid was responding to a question on whether any Covid-19 vaccine should be recognised and considered or only the ones validated by the World Health Organization or any other group.
Shahid said he took Covishield and &lsquo;survived&rsquo; but added that&nbsp; &lsquo;someone else, a medical person' should make that call&rsquo; on recognizing vaccine
India has exported over 66 million vaccine doses to nearly 100 countries through grants, commercial shipments and the COVAX facility.

Professor Sarah Gilbert, creator of AstraZeneca&nbsp;vaccine said that Covid-19 is unlikely mutate into a deadlier variant.&nbsp;
It will eventually just be a 'common cold', just like four other coronaviruses&nbsp;that circulate widely in the air.&nbsp;
Speaking at Royal Medical Society seminar, she also said that work on a tweaked vaccine against Beta variant only gave 'slightly better' immune response. However, data is still being collected on it.&nbsp;
Professor Gilbert's comments come just as Professor Chris Witty, Chief Medical Officer of England warned that non&nbsp;vaccinated children are at a risk of contracting Covid-19 at least once.&nbsp;

'Covid is going to just become a cold': creator of AstraZeneca vaccine, Sarah Gilbert

Professor Sarah Gilbert, the creator of life saving AstraZeneca&nbsp;vaccine has said that Covid-19 will eventually just be a 'common cold'. Watch this report

Professor Sarah Gilbert, the creator of AstraZeneca&nbsp;vaccine has said that Covid-19 is unlikely mutate into a deadlier variant.&nbsp;
She said it will eventually just be a 'common cold', just like four other coronaviruses&nbsp;that circulate widely in the air.&nbsp;
Speaking at Royal Medical Society seminar, she also said that work on a tweaked vaccine against Beta variant only gave 'slightly better' immune response. However, data is still being collected on it.&nbsp;
Gilbert's comments come just as Professor Chris Witty, the Chief Medical Officer of England warned that non&nbsp;vaccinated children are at a risk of contracting Covid-19 at least once.&nbsp;

At a Royal Society of Medicine seminar Professor Gilbert said that Covid-19 will eventually just be a common cold similar to other coronaviruses. The CMO&nbsp;of Eng comments all unvaccinated&nbsp;children to get coronavirus&nbsp;once.&nbsp;

Professor Sarah Gilbert, the creator of AstraZeneca&nbsp;vaccine has said that Covid-19 is unlikely to mutate into a deadlier variant.&nbsp;
It will eventually just be a 'common cold', just like four other coronaviruses&nbsp;that circulate widely in the air, she added.&nbsp;
Speaking at Royal Medical Society seminar, she also said that work on a tweaked vaccine against Beta variant only gave 'slightly better' immune response. However, data is still being collected on it.&nbsp;
Professor Gilbert's comments come just as Professor Chris Witty, Chief Medical Officer of England warned that non&nbsp;vaccinated children are at a risk of contracting Covid-19 at least once.&nbsp;

Total antibody levels start to drop six weeks after complete immunisation with Pfizer and AstraZeneca vaccines, according to study published in The Lancet journal. The study adds the levels can reduce by more than 50 per cent over 10 weeks.
The findings based on data from over 600 people aged 18 and above were consistent across all groups of people regardless of age, chronic illnesses or sex.
The researchers from University College London (UCL) warned protective effects of the vaccines may also begin to wear off, particularly against new variants if the antibody levels carry on dropping at this rate.
The UCL Virus Watch study also found that antibody levels are substantially higher following two doses of the Pfizer vaccine than after two shots of the AstraZeneca preventive, known as Covishield in India.
Further, the study showed that antibody levels were much higher in vaccinated people than those with prior SARS-CoV-2 infection.
The findings support recommendations that adults who are clinically vulnerable, or those aged 70 years or over should be prioritised for booster doses

Pfizer, AstraZeneca vaccine antibody levels may decline after 2-3 months: Lancet study

Total antibody levels start to wane six weeks after complete immunisation with Pfizer and AstraZeneca vaccines, and can reduce by more than 50 per cent over 10 weeks, according to Lancet study

Total antibody levels start to wane six weeks after complete immunisation with Pfizer and AstraZeneca vaccines, and can reduce by more than 50 per cent over 10 weeks, according to Lancet study

Total antibody levels start to drop six weeks after complete immunisation with Pfizer and AstraZeneca vaccines, according to study published in The Lancet journal. The study adds the levels can reduce by more than 50 per cent over 10 weeks.
The findings based on data from over 600 people aged 18 and above were consistent across all groups of people regardless of age, chronic illnesses or sex.
The researchers from University College London (UCL) warned protective effects of the vaccines may also begin to wear off, particularly against new variants if the antibody levels carry on dropping at this rate.
The UCL Virus Watch study also found that antibody levels are substantially higher following two doses of the Pfizer vaccine than after two shots of the AstraZeneca preventive, known as Covishield in India.
Further, the study showed that antibody levels were much higher in vaccinated people than those with prior SARS-CoV-2 infection.
The findings support recommendations that adults who are clinically vulnerable, or those aged 70 years or over should be prioritised for booster doses

AstraZeneca and the University of Oxford on Sunday began new trials to test a modified vaccine against the Beta variant, which first emerged in South Africa, news agency AFP has reported.
The new vaccine has been designed using the same base as the main AstraZeneca shot but with minor genetic alterations to the spike protein based on the Beta variant.
The 'booster' vaccine's trial will involve around 2,250 participants from Britain, South Africa, Brazil and Poland.
Initial data from the trial is expected later this year.
"Testing booster doses of existing vaccines and new variant vaccines is important to ensure we are best prepared to stay ahead of the pandemic," the Oxford Vaccine Group said.
&nbsp;

AstraZeneca testing booster shot against Covid Beta variant

AstraZeneca and the University of Oxford on Sunday began new trials to test a modified vaccine against the Beta variant, which first emerged in South Africa

AstraZeneca and the University of Oxford on Sunday began new trials to test a modified vaccine against the Beta variant, which first emerged in South Africa, news agency AFP has reported.
The new vaccine has been designed using the same base as the main AstraZeneca shot but with minor genetic alterations to the spike protein based on the Beta variant.
The 'booster' vaccine's trial will involve around 2,250 participants from Britain, South Africa, Brazil and Poland.
Initial data from the trial is expected later this year.
&nbsp;
&nbsp;

AstraZeneca and the University of Oxford on Sunday began new trials to test a modified vaccine against the Beta variant, which first emerged in South Africa

AstraZeneca and the University of Oxford on Sunday began new trials to test a modified vaccine against the Beta variant, which first emerged in South Africa, news agency AFP has reported.
The new vaccine has been designed using the same base as the main AstraZeneca shot but with minor genetic alterations to the spike protein based on the Beta variant.
The 'booster' vaccine's trial will involve around 2,250 participants from Britain, South Africa, Brazil and Poland.
Initial data from the trial is expected later this year.
"Testing booster doses of existing vaccines and new variant vaccines is important to ensure we are best prepared to stay ahead of the pandemic," the Oxford Vaccine Group said.
&nbsp;

German Chancellor Angela Merkel received a Moderna Covid-19 vaccine as her second jab, after getting AstraZeneca as the first, a spokesman said Tuesday.
The 66-year-old took her first dose of AstraZeneca's vaccine in April, more than two weeks after German authorities recommended use of the jab only for people aged 60 and over.
German Chancellor Angela Merkel took her first dose of AstraZeneca's vaccine in April, and on June 22, she received Moderna's Covid-19 vaccine as her second shot
Merkel who is stepping down this year after 16 years in power had sparked concerns for her health in 2019 with a series of shaking spells.

Germany Angela Merkel gets Covid vaccine cocktail, AstraZeneca dose followed by Moderna shot

Covid vaccine cocktail: Angela Merkel gets Moderna as second jab after AstraZeneca first dose

<ul>
<li>German chancellor&nbsp;Angela Merkel&nbsp;gets Covid&nbsp;vaccine cocktail</li>
<li>Merkel receives second&nbsp;Moderna dose after first AstraZeneca shot</li>
<li>Merkel&nbsp;took her first dose of AstraZeneca&nbsp;in April and second dose of Moderna&nbsp;in June</li>
</ul>

German Chancellor Angela Merkel became the first world leader to receive a&nbsp;Covid vaccine cocktail shot.
Merkel took her first dose of AstraZeneca's vaccine in April, and on June 22, she received Moderna's Covid-19 vaccine as her second shot.
The 66-year-old took her first dose of AstraZeneca's vaccine in April, more than two weeks after German authorities recommended the use of the jab only for people aged 60 and over.
Merkel who is stepping down this year after 16 years in power had sparked concerns for her health in 2019 with a series of shaking spells. She has however appeared to be in good condition since then.

In UK, most adults under the age of 40 will be given an alternative to the Oxford-AstraZeneca Covid-19 vaccine due to a link with rare blood clots. The country&rsquo;s medicines safety regulator said there have been 242 clotting cases and 49 deaths, with 28.5 million doses of the vaccine administered.
However, the risk is slightly higher in younger age groups. The risk of a clot is roughly one in 100,000 for people in their 40s, but rises to one in 60,000 for people in their 30s. Two in a million people in their 40s died rising to four per million people in their 30s.
The supply of alternative vaccines, including Pfizer and Moderna, has made the decision possible.

Blood clot risks: In UK under 40s to be offered alternative to AstraZeneca Covid vaccine

In UK under 40s to be offered alternative to AstraZeneca Covid vaccine

AstraZeneca&nbsp;vaccine alternative for under 40s in UK
Alternative given due to vaccine's link to blood clots
Risk of a blood clot higher in younger age
Supply of&nbsp;alternative vaccines also facilitates decision
&nbsp;
&nbsp;

In UK, most adults under the age of 40 will be given an alternative to the Oxford-AstraZeneca Covid-19 vaccine due to a link with rare blood clots. The country&rsquo;s medicines safety regulator said there have been 242 clotting cases and 49 deaths, with 28.5 million doses of the vaccine administered.
However, the risk is slightly higher in younger age groups. The risk of a clot is roughly one in 100,000 for people in their 40s, but rises to one in 60,000 for people in their 30s. Two in a million people in their 40s died rising to four per million people in their 30s.
The supply of alternative vaccines, including Pfizer and Moderna, has made the decision possible.

A top American civil rights leader has urged President Joe Biden to release 60 million AstraZeneca vaccine doses for India. The AstraZeneca vaccine has not been approved by the US and is unlikely to be used by the Biden administration.
Joe Biden had recently said that he intended to give AstraZeneca vaccines to other countries. India is currently battling a devastating second wave of the coronavirus pandemic.
At a news conference in Chicago, American civil rights activist Rev Jesse Jackson said he would speak to Biden to immediately release 60 million doses of AstraZeneca vaccines to India.

Top US activist Jesse Jackson urges Joe Biden to give India 6 cr AstraZeneca doses

top American civil rights leader REv&nbsp;Jesse Jackson has urged President Joe Biden to release 6 crore&nbsp;AstraZeneca&nbsp;Covid vaccine doses for India

Top US activist urges Biden to give India 6 cr AstraZeneca doses

A top American civil rights leader has urged President Joe Biden to release 60 million AstraZeneca vaccine doses for India. The AstraZeneca vaccine has not been approved by the US and is unlikely to be used by the Biden administration.
Joe Biden had recently said that he intended to give AstraZeneca vaccines to other countries. India is currently battling a devastating second wave of the coronavirus pandemic.
At a news conference in Chicago, American civil rights activist Rev Jesse Jackson said he would speak to Biden to immediately release 60 million doses of AstraZeneca vaccines to India.

The Biden administration has came under intense pressure from various quarters, including the powerful US Chambers of Commerce, lawmakers and eminent Indian-Americans, to ship AstraZeneca and other Coronavirus (Covid-19) vaccines along with several life-saving medical supplies to India, which is witnessing a deadly surge in coronavirus cases.The head of international affairs at the US Chamber of Commerce said, these vaccine doses will not be needed in the United States, where it's estimated that vaccine manufacturers will be able to produce enough doses by early June to inoculate every American.The US Chambers issued the statement after Indian External Affairs Minister S Jaishankar sought global help in fight against Covid-19.

Biden govt under pressure to ship AstraZeneca vaccine, supplies to India

Biden govt under pressure from US Chamber&nbsp;of Commerce &amp; Indian-American lawmakers to ship AstraZeneca vaccine, supplies to India

Biden&nbsp;govt faces pressure to send vaccine supplies to India&nbsp;
US Chamber of Commerce, Indian-Americans push US govt
These vaccine doses will not be needed in the United States
US can produce enough doses by June to inoculate every American
EAM&nbsp;S Jaishankar sought global help in fight against Covid
&nbsp;

The Biden administration has came under intense pressure from various quarters, including the powerful US Chambers of Commerce, lawmakers and eminent Indian-Americans, to ship AstraZeneca and other Coronavirus (Covid-19) vaccines along with several life-saving medical supplies to India, which is witnessing a deadly surge in coronavirus cases. The head of international affairs at the US Chamber of Commerce said, these vaccine doses will not be needed in the United States, where it's estimated that vaccine manufacturers will be able to produce enough doses by early June to inoculate every American. The US Chambers issued the statement after Indian External Affairs Minister S Jaishankar sought global help in fight against Covid-19.

As India reels under the second wave of coronavirus, there have been calls from several quarters to open vaccination to everyone by removing the age bar. 

Explained: should gap between Covid-19 doses be increased?

Amid growing calls for opening up vaccination for all age groups and reports of shortage of Covid-19 vaccines, will increasing the gap between 2 doses help?&nbsp;

As India reels under the second wave of coronavirus, there have been calls from several quarters to open vaccination to everyone by removing the age bar. But the proposal has also set off alarms about inadequate supply of vaccines. This in turn has led to suggestions that the gap between two doses of a vaccine should be increased so that maximum population can be inoculated with the life-saving jab.
Is the suggestion feasible? Will it reduce the efficacy of the vaccine? Will it help help solve the demand-supply equation?
Before we get to those answers, first let&rsquo;s see how 2-shot vaccines work.
Also Read | <a href="https://www.editorji.com/story/sputnik-v-what-you-need-to-know-about-the-russian-vaccine-1618243022603" target="_blank">Sputnik V: What you need to know about the Russian vaccine</a>
The job of the first jab is to build immunity, generate the necessary anti-bodies, the job of the second is to ramp up the process and re-inforce the immunity. The body doesn&rsquo;t immediately generate immune response after getting the first dose, it&rsquo;s a slow process and usually takes around 3 weeks.
Dr Gangandeep Kang told Indian Express that it can take up to eight weeks or longer for the antibodies to become fully functional and said that gap between two doses should not be less than 3-4 weeks.
Experts say that the risk with giving the second dose too early is that it doesn&rsquo;t give the immune system enough time to react to the first dose so that it can maximise benefits of the second dose.
However, the required interval between the two doses differs from vaccine. Results of Oxford Vaccine Trials reviewed by The Lancet say that a single dose of the <a href="https://www.editorji.com/story/astrazeneca-covid-shot-76-effective-in-updated-us-trial-results-1616650376976" target="_blank">Oxford-AstraZeneca vaccine</a> showed 76% efficacy from day 22 to day 90, which means that efficacy of the drug had not reduced between. The report also suggested 3 months or 12 weeks as an effective gap. Vaccine-maker Pfizer on the other hand has recommended that the gap between jabs of their drug be 3 weeks, and that it should be given after 6 weeks only in special situations.
Also Read | <a href="https://www.editorji.com/story/850-million-doses-of-sputnik-v-covid-vaccine-annually-limited-shots-by-month-end-1618298567193" target="_blank">850 million doses of Sputnik V Covid vaccine annually, limited shots by month-end</a>
In India, while <a href="https://www.editorji.com/story/who-won-t-be-extending-covishield-s-shelf-life-to-9-months-1617962364437" target="_blank">Covishield</a> doses are administered in a gap of 6-8 weeks, the cut-off for Covaxin is 4 weeks. In fact, the interval for Covishield earlier was 4-6 weeks but the govt extended it to 4-8 weeks while saying that the protection offered by the drug is enhanced if given between 6-8 weeks. Though it did add that the gap should not be longer than 8 weeks.
Vaccine expert Dr Gangandeep Kang has told India Express that it is worthwhile to increase the interval if it gives a greater degree of protection and provides good immunity with a single dose. This also solves the problem supply constraints, he added. It gives more time for production of more vaccines.
Though he advised against it if one dose of a 2-shot vaccins does not generate good or required amount of immunity.
Countries like UK, Germany, France and Canada have already increased the gap between 2 doses to accelerate the inoculation drive, ensure maximum efficacy and also to deal with shortage of supplies.
Also Read | <a href="https://www.editorji.com/story/india-gets-third-covid-19-vaccine-sputnik-v-joins-covaxin-covishield-1618282917454" target="_blank">India gets third Covid-19 vaccine, Sputnik V joins Covaxin &amp; Covishield</a>
France is set to extend the period for mRNA vaccines to 6 weeks from 4 weeks starting April 14. In Germany, the time period has been increased to 12 weeks for the Oxford drug. In UK, the gap was stipulated at 10-12 weeks for all vaccines but the experts called upon them to reduce it for Pfizer. Canada administers it Covid-19 vaccine doses at a gap of 4 months.
Now, given that there is urgent need for maximising vaccination in India that is not helped by the reports of shortfall in vaccine, extending the time between 2 doses of Covishield, which has a recommended gap of 12 weeks, does seem to present itself as a good option. However, <a href="https://www.editorji.com/story/it-s-safe-made-in-india-covaxin-gets-thumbs-up-from-lancet-1615274532292" target="_blank">Covaxin</a> unlike Covishield is an inactivated vaccine and Dr Kang says that such vaccines do better with shorter intervals.
Whether the Indian govt increase the interval between two jabs are not, the purpose of these vaccines is to decrease the severity of disease, prevent hospitalisation and reduce deaths due to <a href="https://www.editorji.com/covid-19" target="_blank">Covid-19</a>. They do not prevent you from contracting the disease all together.
So mask up, wash your hands and maintain appropriate social and physical distance.
Also Read | <a href="https://www.editorji.com/story/know-your-vaccines-how-do-sputnik-v-covaxin-and-covishield-work-1618306290653" target="_blank">Know your vaccines: How do Sputnik V, Covaxin and Covishield work?</a>

astrazeneca vaccine

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