The Phase II clinical trial of the Oxford Covid-19 vaccine candidate which is being manufactured by the Serum Institute of India began at a medical college and hospital in Pune on Wednesday. Two male volunteers were administered the vaccine at Bharti Vidyapeeth's Medical College and Hospital. Five volunteers had enrolled themselves for the trial after the doses were received from the SII on Tuesday. Of them, the reports of three volunteers' antibodies test came out positive, so they became ineligible for the trial. SII, the world's largest vaccine maker, has signed an agreement to manufacture the potential vaccine developed by the Jenner Institute of Oxford University in collaboration with British-Swedish pharma company AstraZeneca.