Why won't the Pfizer and Moderna vaccines work for India? Pfizer and Moderna vaccines are both mrna vaccines, which need to be stored at-20 C to -80C for them to be efficient. India has a vaccine cold chain of 2 - 8 degrees Celsius storage which was used for oral polio vaccine. mRNA vaccines, which need extremely cold temperatures, may need additional storage and transportation. Which is the best vaccine for India then? Watch Prof Vineeta Bal, Dept of Biology, IISER Pune explain.