Lauren Glynn, McKinley Moore, Avalynn Luciano and Chloe Grimes all met around the age of seven, while they were undergoing treatment for cancer at Johns Hopkins All Children's Hospital in Florida.
In the hospital, they sang together and played ring-around-the-rosy and kept each other company while undergoing brutal treatment.
Since that time in 2016, the girls have held an annual reunion every year since donning t-shirts that say "survivor" with gold tutus.
When the coronavirus pandemic made it impossible to organise an in-person reunion, the moms decided to take the online route!
The four friends told each other they miss one another and talk about how many teeth they had lost since they last met.