17-year-old Palmeiras attacker Endrick received his maiden international call-up as Brazil included the teenage sensation in its squad for World Cup qualifiers against Argentina and Colombia later this month.
Casemiro and Neymar missed out due to injuries while Tottenham attacker Richarlison was left out.
Endrick, who will join Real Madrid next summer when he turns 18, has scored 3 goals in his last two games for Brazilian giants Palmeiras.
Brazil face Colombia in Barranquilla on November 16 and hosts World Cup champion Argentina at Maracana Stadium five days later.
Argentina leads South American qualifying with 12 points. Brazil is third with 7 points after a home draw with Venezuela and a 2-0 loss at Uruguay last month.
Coach Fernando Diniz is under pressure to hold the job until June when it is hoped Carlo Ancelotti will take over.
Brazil Squad
Goalkeepers: Alisson (Liverpool), Ederson (Manchester City), Lucas Perri (Botafogo).
Defenders: Emerson Royal (Tottenham), Carlos Augusto (Inter Milan), Renan Lodi (Marseille), Bremer (Juventus), Gabriel Magalhães (Arsenal), Nino (Fluminense), Marquinhos (Paris Saint-Germain).
Midfielder: André (Fluminense), Bruno Guimarães (Newcastle), Douglas Luiz (Aston Villa), Joelinton (Newcastle), Raphael Veiga (Palmeiras), Rodrygo (Real Madrid).
Forwards: Endrick (Palmeiras), Gabriel Jesus (Arsenal), Gabriel Martinelli (Arsenal), João Pedro (Brighton), Paulinho (Atlético Mineiro), Pepê (Porto), Raphinha (Barcelona), Vinicius Junior (Real Madrid).